Building better probiotics

I think most everyone is aware of probiotics, and, judging by our discussions here, many of you take them. A problem is that we don't really know how to target specific probiotics to a particular microbiome situation, meaning that not every probiotic works for everyone. In some cases, I think we do the equivalent of dropping a tropical fish into the Arctic Ocean. THIS ARTICLE from Forbes looks at how synthetic biology is attempting to engineer better probiotics